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    我々のAIへの挑戦は、

    ここから急加速。

    2026年4月1日、サイエンスパーク株式会社 AI研究所 始動
    世界最高峰の知と実装力が結集し、今のAIが抱える矛盾に挑みます。 

     Publications 

    Letter 採択

     平均インパクトファクター「5」を超える学術誌に年間30編を超えるレターを掲載。 

    39
    サイエンスパーク論文数

    ジャーナル一覧

    European Urology Oncology
    IF = 9.3
    NeuroToxicology
    IF = 3.9
    Fuel
    IF = 7.4
    Briefings in Bioinformatics
    IF = 6.8
    Microbial Risk Analysis
    IF = 4
    Psychiatry Research
    IF = 3.9
    Clinical Nutrition ESPEN
    IF = 2.6
    Cancers
    IF = 4.4
    Journal of Dairy Science
    IF = 4.4
    Annals of Epidemiology
    IF = 3
    The Journal of Pain
    IF = 4
    Veterinary Microbiology
    IF = 2.7
    Canadian Journal of Cardiology
    IF = 5.3
    Clinical Oncology
    IF = 3
    The Journal of Thoracic and Cardiovascular Surgery
    IF = 4.4
    Clinical Lung Cancer
    IF = 3.3
    Computer Methods and Programs in Biomedicine
    IF = 4.8
    Ultrasound in Medicine & Biology
    IF = 2.6
    European Neuropsychopharmacology
    IF = 6.7
    Radiotherapy and Oncology
    IF = 5.3
    Neuroscience
    IF = 3.9
    Environmental Modelling & Software
    IF = 4.6
    Journal of Clinical Lipidology
    IF = 4.6
    Ultrasound in Medicine & Biology
    IF = 2.6
    Journal of Cardiothoracic and Vascular Anesthesia
    IF = 2.1
    Food Chemistry
    IF = 9.8
    Environmental Research
    IF = 7.7
    European Journal of Cancer
    IF = 7.1
    Journal of Affective Disorders
    IF = 4.9
    Academic Radiology
    IF = 3.1
    Building and Environment
    IF = 7.6
    International Journal of Gynecological Cancer
    IF = 4.7
    European Journal of Radiology
    IF = 3.3
    Australian Critical Care
    IF = 2.7
    Computers in Biology and Medicine
    IF = 6.3
    Scripta Materialia
    IF = 5.6
    Science of The Total Environment
    IF = 8
    Journal of Hazardous Materials
    IF = 11.3
    European Journal of Surgical Oncology
    IF = 2.9

    論文リスト

    No. Title Authors Journal Year DOI
    40 Re: Jurczok N, Dernbach G, Ebner B, et al. Multiregional immune profiling reveals prognostic patterns in bladder cancer. Eur Urol Oncol. In press. http://dx.doi.org/10.1016/j.euo.2025.12.006 Yoshida Kiyo, Oka Souichi, Takefuji Yoshiyasu European Urology Oncology 2026 10.1016/j.euo.2026.03.027
    39 Reconsidering principal component analysis in neurodevelopmental studies: A call for advanced frameworks Oka Souichi, Ono Ryota, Takefuji Yoshiyasu NeuroToxicology 2026 10.1016/j.neuro.2026.103456
    38 Limits of SHAP feature importance in XGBoost–SOL Surrogates for catalytic Cracking: Correlation-Driven Bias, stability Diagnostics, and the Need for unsupervised validation Ghale Suyam, Oka Souichi, Takefuji Yoshiyasu Fuel 2026 10.1016/j.fuel.2026.139411
    37 Addressing biases and limitations in feature attribution for circRNA modification profiling Oka Souichi, Takemura Kota, Takefuji Yoshiyasu Briefings in Bioinformatics 2026 10.1093/bib/bbag168
    36 Interpreting genomics-driven microbial criteria: Toward robust and transparent risk models Oka Souichi, Yoshida Kiyo, Takefuji Yoshiyasu Microbial Risk Analysis 2026 10.1016/j.mran.2026.100372
    35 Breaking the spline: Why distributed lag non-linear models miss thresholds in environmental psychiatry Oka Souichi, Yamazaki Takuma, Takefuji Yoshiyasu Psychiatry Research 2026 doi.org/10.1016/j.psychres.2026.117104
    33 Interpreting IDDSI-linked nutrient patterns: From correlations to compositional modules Oka Souichi, Yoshida Kiyo, Takefuji Yoshiyasu Clinical Nutrition ESPEN 2026 10.1016/j.clnesp.2026.102982
    32 Revisiting AI Interpretability in Precision Oncology: Why Predictive Accuracy Does Not Ensure Stable Feature Importance Oka Souichi, Takefuji Yoshiyasu Cancers 2026 10.3390/cancers18040593
    31 Letter to the Editor: Addressing the limitations of principal component analysis in dairy flavor research Oka Souichi, Inoue Nobuko, Takefuji Yoshiyasu Journal of Dairy Science 2026 10.3168/jds.2025-27656
    30 Towards reliable feature interpretation in machine learning-based longevity prediction Oka Souichi, Takahashi Yoshiki, Takefuji Yoshiyasu Annals of Epidemiology 2026 10.1016/j.annepidem.2026.01.005
    29 Beyond linear assumptions: Advancing lipidomic analysis in localized provoked vulvodynia Oka Souichi, Yoshida Kiyo, Takefuji Yoshiyasu The Journal of Pain 2026 10.1016/j.jpain.2025.106179
    28 From bias to reliable insight: Rethinking feature importance in microbiome analytics Oka Souichi, Yoshida Kiyo, Takefuji Yoshiyasu Veterinary Microbiology 2026 10.1016/j.vetmic.2025.110838
    27 Feature Importance Bias: Addressing Interpretability Issues in Tree-Based Acute Myocardial Infarction Risk Models Oka Souichi, Takemura Kota, Takefuji Yoshiyasu Canadian Journal of Cardiology 2026 10.1016/j.cjca.2025.11.032
    26 Beyond Parametric Boundaries: Rethinking the Distributed Lag Nonlinear Model in Meteorological Modelling for Oncology Emergencies Oka S., Yoshida K., Takefuji Y. Clinical Oncology 2026 10.1016/j.clon.2025.103970
    25 Beyond linear and parametric assumptions: A call for robust models in donor extracellular vesicles transcriptomics Oka Souichi, Yoshida Kiyo, Takefuji Yoshiyasu The Journal of Thoracic and Cardiovascular Surgery 2026 10.1016/j.jtcvs.2025.09.041
    24 Revisiting AI Model Interpretability in Lung Cancer Screening: Challenges in Balancing Predictive Performance and Reliability Oka Souichi, Takefuji Yoshiyasu Clinical Lung Cancer 2026 10.1016/j.cllc.2025.09.005
    23 Beyond predictive accuracy: Statistical validation of feature importance in biomedical machine learning Oka Souichi, Inoue Nobuko, Takefuji Yoshiyasu Computer Methods and Programs in Biomedicine 2025 10.1016/j.cmpb.2025.109085
    22 Towards Reliable Feature Importance in Hashimoto's Thyroiditis Prediction: Reconstructing Machine Learning Frameworks Oka Souichi, Takefuji Yoshiyasu Ultrasound in Medicine & Biology 2026 10.1016/j.ultrasmedbio.2025.09.008
    21 A call for more robust and interpretable models in predicting treatment-resistant depression Oka Souichi, Takemura Kota, Takefuji Yoshiyasu European Neuropsychopharmacology 2025 10.1016/j.euroneuro.2025.09.012
    20 Towards reliable feature interpretation in machine learning-based acute diarrhoea toxicity assessment Oka Souichi, Takahashi Yoshiki, Takefuji Yoshiyasu Radiotherapy and Oncology 2025 10.1016/j.radonc.2025.111140
    19 Reassessing PCA-based characterization of spiral ganglion neuron cell lines Oka Souichi, Ono Ryota, Takefuji Yoshiyasu Neuroscience 2025 10.1016/j.neuroscience.2025.09.036
    18 Pitfalls of XAI interpretation in environmental modeling: A warning on model bias in air quality data analysis Oka Souichi, Yamazaki Takuma, Takefuji Yoshiyasu Environmental Modelling & Software 2025 10.1016/j.envsoft.2025.106700
    17 Enhancing lipoprotein(a) association studies: A complementary approach to principal component analysis Oka Souichi, Inoue Nobuko, Takefuji Yoshiyasu Journal of Clinical Lipidology 2025 10.1016/j.jacl.2025.08.021
    16 Methodological Concerns in Radiomics: Addressing Bias in LASSO and SHAP for Thyroid Tumor Analysis Iwata Naoki, Oka Souichi, Takefuji Yoshiyasu Ultrasound in Medicine & Biology 2025 10.1016/j.ultrasmedbio.2025.08.016
    15 Clinical Machine Learning Pitfalls: Reliability of Feature Importance in Prediction of Continuous Renal Replacement Therapy in Acute Type A Aortic Dissection Assessment Oka Souichi, Takefuji Yoshiyasu Journal of Cardiothoracic and Vascular Anesthesia 2025 10.1053/j.jvca.2025.08.035
    14 Addressing Bias in machine learning feature importance for food quality assessment Oka Souichi, Yamazaki Takuma, Takefuji Yoshiyasu Food Chemistry 2025 10.1016/j.foodchem.2025.146171
    13 Beyond model-specific biases: An explainable multifaceted approach for robust PM10 source apportionment Oka Souichi, Yamazaki Takuma, Takefuji Yoshiyasu Environmental Research 2025 10.1016/j.envres.2025.122656
    12 Letter Re: Development of an artificial intelligence-generated, explainable treatment recommendation system for urothelial carcinoma and renal cell carcinoma to support multidisciplinary cancer conferences Oka Souichi, Yamazaki Takuma, Takefuji Yoshiyasu European Journal of Cancer 2025 10.1016/j.ejca.2025.115733
    11 Reassessing lipid-mood disorder associations: The limitations of PCA for nonlinear patterns Ogawa Soki, Oka Souichi, Takefuji Yoshiyasu Journal of Affective Disorders 2025 10.1016/j.jad.2025.120024
    10 Robust Feature Attribution in Radiomics: A Call for Multi-faceted Methodologies Oka Souichi, Takefuji Yoshiyasu Academic Radiology 2025 10.1016/j.acra.2025.07.048
    9 Feature importance in building machine learning: Beyond model-dependent interpretations Oka Souichi, Yamazaki Takuma, Takefuji Yoshiyasu Building and Environment 2025 10.1016/j.buildenv.2025.113493
    8 Correspondence on “Large-scale analysis to identify risk factors for ovarian cancer” by Madakkatel et al Oka Souichi, Takefuji Yoshiyasu International Journal of Gynecological Cancer 2025 10.1016/j.ijgc.2025.102000
    7 Complementing interpretable machine learning with synergistic analytical strategies for thyroid cancer recurrence prediction Oka Souichi, Takefuji Yoshiyasu European Journal of Radiology 2025 10.1016/j.ejrad.2025.112308
    6 Re-evaluating structural equation modelling in nursing research: Insights from compassion fatigue and empowerment in Chinese intensive care units Egawa Mana, Oka Souichi, Takefuji Yoshiyasu Australian Critical Care 2025 10.1016/j.aucc.2025.101292
    5 Letter to the Editor: Complementary statistical approaches for interpreting machine learning feature importance in osteoporosis risk Oka Souichi, Yamazaki Takuma, Takefuji Yoshiyasu Computers in Biology and Medicine 2025 10.1016/j.compbiomed.2025.110710
    4 Comments on "Toward prediction and insight of porosity formation in laser welding: A physics-informed deep learning framework" Oka Souichi, Takefuji Yoshiyasu Scripta Materialia 2025 10.1016/j.scriptamat.2025.116857
    3 Letter to the Editor regarding “Prediction of PFAS bioaccumulation in different plant tissues with machine learning models based on molecular fingerprints” by Song et al. (2024), Sci. Total Environ. 950 175091 Oka Souichi, Takefuji Yoshiyasu Science of The Total Environment 2025 10.1016/j.scitotenv.2025.179714
    2 Comments on "Dialogue between algorithms and soil: Machine learning unravels the mystery of phthalates pollution in soil" by Pan et al. (2025) Oka Souichi, Takefuji Yoshiyasu Journal of Hazardous Materials 2025 10.1016/j.jhazmat.2025.138366
    1 Comment on "Optimized machine learning model for predicting unplanned reoperation after rectal cancer anterior resection" Oka Souichi, Takefuji Yoshiyasu European Journal of Surgical Oncology 2025 10.1016/j.ejso.2025.110025

    好奇心は、止まらない。

    AI研究所は、今のAIが抱える矛盾に真正面から向き合い、その成果をビジネスの実装へとつなげていきます。 


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